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Perlane® is a popular dermal filler injection that is an excellent treatment for smile lines, deep folds, depressed scars, and lip augmentation. Made of hyaluronic acid, a natural substance, Perlane® fills up the skin like normal tissues, making the modeling of facial contours appear perfectly natural.

It is a safe treatment that simply supplements the body’s age-depleted hyaluronic acid and softens the effects of aging. Since Perlane® is a natural substance, it is eventually broken down in the body and, therefore, not permanent. The injections are long-lasting, however.

A sister product of Restylane®, Perlane® is a clear gel that is slightly thicker than Restylane®. Because of its thickness, it can be injected into a deeper layer of the skin. Perlane® is made from a non-animal acid gel, so no allergy skin test is required.

The skill of your injector is vital for a natural-looking result. Your injector must have the training and experience to know the proper dosage and where to place the injections. At Comprehensive Dermatology Center of Pasadena, we have many years of experience with Perlane® and other dermal fillers. We know how these products work in the skin and can recommend whether Perlane® or a combination of fillers will give you the look you want.

What Can Perlane® Do For Me?

Perlane® is much like a non-surgical face lift for people with moderate to severe effects of aging. It can improve:

  • Facial wrinkles
  • Fine lines around the lips, mouth, nose, and forehead
  • Acne scars or other types of scars
  • Nasolabial folds from the nose to the mouth
  • Cheek depressions
  • Hollows around the eyes
  • Drooping mouth corners
  • Thin lips through lip augmentation

What is a Perlane® Treatment Like?

A fine needle is used to inject Perlane®, and the formula includes Lidocaine, which helps to numb the injection areas. We also apply a topical anesthetic to ensure your comfort.

Including the time required for the topical anesthetic to take effect, your appointment for Perlane® injections should last no more than an hour.

How Long Do Perlane® Results Last?

Perlane® is a long-lasting wrinkle filler, but it is not permanent. In many patients, the results last 9-12 months. It also stimulates your body’s production of collagen for continued improvement during the months following your treatment.

What Will I Experience While Recovering From Perlane®?

You can return to work and other normal activities immediately after your Perlane® appointment. You may experience some minor bruising, redness, itching, and swelling at the injection sites, however, which usually last just a few days. Any discoloration can be covered with makeup.

If Perlane® is used for lip enhancement, your lips may swell or look uneven for a few days before the product settles properly.

You can see some results of Perlane® immediately, and these results will continue to improve as your body produces more collagen.


Our treatment suites are equipped with the latest dermatological lasers, for advanced, safe, comfortable treatment of your skin's medical and cosmetic needs. Our in-house Acne Treatment Center offers complete care for all ages and acne stages. We offer a full line of skin care products designed to suit your unique...

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